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Synbiotic-P2K: A Probiotic for Weight Loss

Weight gain and obesity are problems that more and more people are facing, especially with today’s modern lifestyle and diet. More than half of the US population is considered overweight, and at least one third is considered obese. The condition of obesity has many lifelong and devastating health consequences, not to mention the effect on one’s own state of mind and self-esteem.

PharmaTerra developed Synbiotic-P2K specifically to address weight loss. A synbiotic is a probiotic that is combined with prebiotics, which are plant fibers that both serve as food for the probiotic bacteria, and assist the probiotics in doing their job. When taking probiotics alone, the bacteria tend to die off quickly in the gut, and you need to take more of the probiotics to keep the effects going. With synbiotics, the probiotics have their own food source, and this allows them a better survival rate over time in the gut, when compared to taking probiotics alone.

Synbiotic-P2K contains specially acting probiotics and prebiotics that have both been shown to target weight loss, among other properties. The specific bacterial strains that make it up, which are l.reuteri, l.gasseri and b.lactis, have unique properties.

L.reuteri has been shown to reduce LDL cholesterol levels significantly.* In 2012, a McGill University study of 127 patients showd that over 9-weeks, LDL cholesterol decreased by 11.64% and total cholesterol decreased by 9.14% with l.reuteri supplementation.1 High cholesterol has been associated with poor cardiovascular health, which in turn goes hand in hand with obesity.*

L. gasseri has been shown to speed up metabolism and encourage weight loss.* In 2010 the European Journal of Clinical Nutrition found that l.gasseri reduced abdominal body fat and waist size.2 In 2013 the British Journal of Nutrition published a study which showed that obese adults who took the strain showed an 8% drop in body weight over a 12-week period.3*

B.lactis has also been shown to have weight loss properties.* In a 2013 study published in the International Journal of Food Science & Nutrition, patients taking b.lactis showed improved basal metabolic indexes, reduced waist sizes and lipid levels.4* Also in 2013, two separate studies, one in Japan and another in Korea, showed participants having loss of visceral fat and reduced waist circumferences after taking b.lactis over time 5,6.* The Japanese study showed that the improvements were lost after the participants stopped taking the probiotic, which tells us just how important and critical probiotics are to our health.*

As prebiotic fibers, we added two other powerful weight loss supplements - Phase 2 White Kidney Bean Extract and Glucomannan from Konjac Root. Phase 2 is one of the most studied carbohydrate blockers available today. It has been shown to reduce the enzymatic digestion and absorption of starches by up to 66%.* In 2007, a study published in the International Journal of Medical Science showed that participants who took Phase 2 lost on average more than 10% of body fat mass and showed reduced waist circumferences.7*

Glucomannan (Konjac Root) is a fiber. It acts as a prebiotic that helps probiotics grow in the gut.* Also, it has been shown in many studies to aid in weight loss, and also in the maintenance of blood sugar levels that are already within the normal range.*

A 2005 study in Norway published by the International Medical Journal of Experimental and Clinical Research showed that participants taking Konjac root showed an average of 1.75lbs of weight loss per week.8*

Probiotic-P2K is recommended as part of an overall program of diet, exercise and lifestyle to assist in maintaining overall physical health and wellbeing.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, cure or diagnose any disease.



  1. Jones ML1, Martoni CJ, Prakash S., Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. Eur J Clin Nutr. 2012 Nov;66(11):1234-41
  2. Kadooka Y, Sato M, Ogawa A, et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. Br J Nutr. 2013 Nov 14;110(9):1696-703. doi: 10.1017/S0007114513001037.
  3. Kadooka Y, Sato M, Imaizumi K, et al. Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial. Eru J Clin Nutr. 2010 Jun;64(6):636-43. doi: 10.1038/ejcn.2010.19.
  4. Safavi M, Farajian S, Kelishadi R, Mirlohi M, Hashemipour M. The effects of synbiotic supplementation on some cardio-metabolic risk factors in overweight and obese children: a randomized triple-masked controlled trial. Int J Food Sci Nutr 2013; 64(6): 687-693.
  5. Kadooka Y, Sato M, Ogawa A, Miyoshi M, Uenishi H, Ogawa H et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomised controlled trial. Br J Nutr 2013; 110(9): 1696-1703.
  6. Jung SP, Lee KM, Kang JH, Yun SI, Park HO, Moon Y et al. Effect of Lactobacillus gasseri BNR17 on Overweight and Obese Adults: A Randomized, Double-Blind Clinical Trial. Korean J Fam Med 2013; 34(2): 80-89.
  7. Celleno L, Tolaini, MV, D’Amore A, Perricone, NV, Preuss, HG, A Dietary Supplement Containing Standardized Phaseolus Vulgaris Extract Influences Body Composition of overweight Men and Women, International Journal of Medical Sciences, 2007
  8. Birketvedt GS1, Shimshi M, Erling T, Florholmen J., Experiences with three different fiber supplements in weight reduction. Med Sci Monit. 2005 Jan;11.






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